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Our understanding of the ‘tree of life’, with powerful implications for human genetics, human health and our own human nature, has recently completely changed.This book is about a new method of telling the story of life on earth – through molecular phylogenetics. It involves a fairly simple method – the reading of the deep history of life by looking at the variation in protein molecules found in living organisms. For instance, we now know that roughly eight per cent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection.In The Tangled Tree, acclaimed science writer David Quammen chronicles these discoveries through the lives of the researchers who made them – such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about ‘mosaic’ creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.Quammen explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life – including where we humans fit into it. Thanks to new technologies, we now have the ability to alter even our genetic composition – through sideways insertions, as nature has long been doing. The Tangled Tree is a brilliant exploration of our transformed understanding of evolution and of life’s history itself.
A cutting-edge examination of what it means to be human and to have a 'self' in the face of new scientific developments in cloning, gene-splicing and neural downloading.After seeing his own cells used to grow clumps of new neurons – essentially mini-brains – Philip Ball begins to examine the concepts of identity and consciousness. Delving into humanity's deep evolutionary past to look at how complex creatures like us emerged from single-celled life, he offers a new perspective on how humans think about ourselves. In an age when we are increasingly encouraged to regard the 'self' as an abstract sequence of genetic information, or as a pattern of neural activity that might be 'downloaded' to a computer, I return us to the body – to flesh and blood – and anchor a conception of personhood in this unique and ephemeral mortal coil. How to Build a Human brings us back to ourselves – but in doing so, it challenges old preconceptions and values. It asks us to rethink how we exist in the world.
The New Naturalist editors believe this to be the greatest general work on the subject ever written.Professor Alistair Hardy is truly obsessed by animals of the sea – devotedly enthusiastic about the nature of their adaptations and life histories, brilliantly critical in the examination of their mysteries, acutely lucid (and at the same time highly artistic) in his descriptions of them in his arresting plates.To describe the relatively unknown and mysterious world of plankton is a task that the greatest of marine zoologists might boggle at. Yet the plankton is to the sea what vegetation is to the land. The study of plankton is a complex discipline which few amateur naturalists have had the privilege to enjoy. Never before has such a synthesis of knowledge been attempted in a community of animals so mysterious, yet so important. Professor Hardy has grasped this problem in a new and exciting way; and at least the common reader can discern the pattern of life that dominates two-thirds of the world’s surface.
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